Abstract Background A lack of available data and statistical code being published alongside journal articles provides a significant barrier to open scientific discourse, and reproducibility of research.Information governance restrictions inhibit the active dissemination of individual level data to accompany published manuscripts.Realistic, high-fid
Cancer is characterised by uncontrolled proliferation and prolonged cell survival.In some cases, tumour formation is the result from aberrant activity of various cell-cycle regulators leading to chromosome instability or from alteration of the apoptosis Gas Hobs pathway.Ovarian cancer is an entity in which cell-cycle alterations are common.P53, a k
Abstract Background Microarray analysis allows the simultaneous measurement of thousands to millions of genes or sequences across tens to thousands of different samples.The analysis of the resulting data tests the limits of existing bioinformatics computing infrastructure.A solution to this issue is to use High Performance Computing (HPC) systems,